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To put that in perspective, a 10 mg/kg dose in a 250-g rat, scaled allometrically to a 70-kg human using the FDA's body surface area conversion factor of 6.2, translates to roughly 1.6 mg/kg, or 112 mg for a 70-kg person 7
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It is also synthesized in the placenta in pregnant women and can be found in high concentrations in breast milk.567 One of the major roles of inositol in the body is the production of inositol triphosphate, which is an essential second messenger for hormones such as insulin and follicle stimulating hormone.6 Choline Choline is an essential nutrient that plays a key role in a number of metabolic pathways in the human body
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