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Studies tracking body composition show semaglutide users lose approximately 7580% fat and 2025% lean mass, compared to 5050 splits in diet-only groups

Combination therapy was considered appropriate for adults with persistent kidney disease progression, high cardiovascular risk or suboptimal metabolic control

Research shows that GLP-1 agonists help protect muscle tissue during weight loss, and muscle tissue burns more calories than fat tissue even at rest

Ethical aspects As this is an integrative review based exclusively on secondary data in the public domain, this study did not involve direct experimentation with humans or the collection of individual information