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Unlike SADI, OAGB connects the stomach to the intestine, not two parts of the intestine

Semaglutide, for example, includes a fatty acid side chain that binds to albumin in the bloodstream, protecting it from enzymatic degradation and extending its half-life to approximately one week

Use of SGLT-2 inhibitors has been associated with a ~2-fold increased risk for limb amputation when compared with the use of sulfonylureas, metformin, and thiazolidinediones (Chang et al, 2018)

Repeated inadvertent ingestion of supratherapeutic doses may be especially dangerous, due to subacute depletion of hepatic glutathione stores