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Resveratrol (3,3,3-triydroxy-trans-stilbene), a phenol derived from the root of knotweed (Polygonium cuspidatum), found in Japan and China [335]

This should only be done under medical guidance, following a consultation to assess suitability

Paracetamol (maximum 4 g daily) is a safe first-line option for most patients, whilst ibuprofen (maximum 1.2 g daily for over-the-counter use) may be used if paracetamol proves insufficient, provided you have no contraindications such as kidney disease or gastric ulcer history

It is an effective tool for those who have struggled with weight despite their best efforts with diet and exercise alone