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To verify this hypothesis, we upregulated the expression of VRK2 in PC cells (PANC-1 cells and BxPC-3 cells) and examine the expression of SLC7A11 at whole cell and PM levels

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Changes in GSH levels with time post dose were calculated as the difference in GSH/Cr peak ratios for each subject at each time point (GSH/Cr post dose GSH/Cr baseline ), or similarly, the difference in absolute GSH for each subject at each time point