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Figure 7 Discussion AX is a widely used antibiotic and one of the most frequently involved in allergic reactions

Most of the research has been aimed at disentangling the effects of specific mechanisms while their interaction received little attention so far

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Important safety considerations include a boxed warning for thyroid C-cell tumors (contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2), and pregnancy avoidance (with a 2-month washout period before conception)