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Downstream signaling from hypothalamic AgRP/NPY/GABA-secreting neurons is considered redundant, meaning that selective stimulation of individual downstream projection areas is sufficient to suppress appetite

Because roughly 95% of serotonin is produced in the gut, ongoing microbiome imbalance and slowed digestion may influence the gut-brain connection in ways researchers are only beginning to understand

Understanding these metabolic disruptions can guide the development of targeted treatments and improve management strategies, ultimately enhancing the clinical outcomes for these patients

The article says body aches alone rarely warrant immediate discontinuation, but should be reported to your provider at the next check-in, or sooner if severe