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Later, in June 2021 , the FDA approved a higher-dose formulation named Wegovy , explicitly t argeted at chronic weight management in patients without diabetes

Sustained weight management remains a critical challenge, but there is hope that newer, more affordable strategies to support long-term weight loss maintenance will emerge in the coming years. Studies have also suggested the use of tirzepatide and other weight-loss drugs in people with heart conditions reduces the risk of hospitalisation for heart failure or death from any cause

Contact your GP or IBD team promptly if you experience worsening gastrointestinal symptoms, as distinguishing between medication side effects and a Crohn's flare requires clinical assessment

With tirzepatide, additional barrier contraception may be needed after starting or increasing the dose, as it can reduce the absorption of oral contraceptives