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For example, dysbiosis of the esophageal/intestinal microbiome and elevation of peripheral blood LPS can regulate ferroptosis in the esophageal epithelium by increasing ACSL4 expression, serum ferritin secretion, and iron accumulation [95]

A 2021 study published in PLoS Biology demonstrated that specific strains of gut bacteria can metabolize orally administered 5-HTP into a novel molecule called 5-hydroxyindole (5-HI)

Because of the potential risks of high-dose magnesium supplementation, especially in those with impaired kidney function, supplementation with magnesium should be conducted under medical supervision