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doi: 10.1080/03007995.2018.1519503

Safety: Preclinical studies show low toxicity across animal models (PubMed 32334036)

Common types of MC4R dysfunction Many variants (e.g., Ser127Leu) exhibit multiple concurrent functional defects, and the majority follow a dominant inheritance pattern consistent with haploinsufficiency [29]

Archived from the original on 29 October 2010