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In the meantime, here are some alternative peptides that have senolytic properties: 5-Amino 1MQ, MOTS-C, Epitalon, and Humanin
Direct hormonal effects: GLP-1 medications don't replace or significantly alter estrogen or progesterone levels Indirect benefits: Weight loss from GLP-1s may improve hormonal imbalances related to excess body fat Key distinction: GLP-1s and HRT work through entirely different mechanisms, which is why combining them may offer complementary benefits What research shows about using HRT and GLP-1 together Emerging research suggests combining HRT with GLP-1 medications may produce better weight loss outcomes than either approach alone, with tirzepatide showing 20.9% weight reduction at 72 weeks in clinical studies
Artmed Nicassio L, Fracasso F, Sirago G, Musicco C, Picca A, Marzetti E, Calvani R, Cantatore P, Gadaleta MN, Pesce V (2017) Dietary supplementation with acetyl- l -carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats
Tell your healthcare provider if you are taking any medications to treat diabetes, including sylfonylureas or insulin
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