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Safety profiles for once-weekly Ozempic (semaglutide) injection and once-daily Ozempic pill (semaglutide) injection and once-daily Ozempic pill Safety and tolerability evaluated across clinical trials Rates of GI symptoms across placebo-controlled trials with Ozempic injection and semaglutide tablets 1,2,a The most common adverse reactions reported in 5% of patients taking Ozempic injection and Ozempic tablets are nausea, vomiting, diarrhea, abdominal pain, and constipation