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demonstrate that pitavastatin induces ferroptosis in malondialdehyde (MDA)-MB-231 triple-negative breast cancer cells via mevalonate pathway inhibition, with exogenous mevalonate supplementation partially reversing pitavastatin-induced cytotoxicity and the reduced expression of GPx4/FSP1 (Tang W.-J
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If the liver is not functioning properly, older hormones can recirculate into the bloodstream in an even more toxic form than when they originally entered the liver
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