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- 5-Amino-1MQ is a research compound studied in models involving NNMT pathway activity, metabolic signaling, adipocyte biology, NAD+-related pathway research, energy-balance models, and body-composition research

Whilst attractive as a theory, it should, nevertheless, be borne in mind that the majority of the studies cited above have been carried out in rodents or have examined isolated islets/-cells under in vitro or ex vivo conditions, and whether a local pancreatic DPP-4/GLP-1 system plays an important role in normal human physiology or in the pharmacological effect of DPP-4 inhibitors is not clear