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Cardiometabolic Burden in Serious Mental Illness Schizophrenia, major depressive disorder, bipolar disorder (BD), and other SMIs are severe, prevalent, and lifelong conditions that are major contributors to disability, reduced healthspan, and diminished social and economic participation, particularly in younger populations

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Incretins also activate receptors in the brain that promote feelings of fullness and reduce appetite an added benefit for individuals who need to lose weight

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