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Hereditary or acquired defects in the transport mechanisms are the major cause of LC deficiency, leading to pathologies such as cardiomyopathy and skeletal muscle myopathy

135 Dihydroartemisinin can significantly inhibit the viability of leukemia cells, causing cell cycle G0/G1 phase arrest and ferroptosis, and the mechanism may be related to inducing autophagy and accelerating ferritin degradation by regulating AMP-activated kinase (AMPK)/mTOR/p70S6k signaling pathway

Journal of Biological Chemistry 261 (25): 11880-11889

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