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Not only that, but the 2005 article concludes by emphasizing the importance of using breed-specific VHS values, and even individual dog variations in heart size and vertebral length, in order for the VHS method to work at all - two things that the EPIC Study investigators clearly never had any intention of taking into account

Four hours after treatment, there was a six-fold increase in periportal cells and a four-fold increase in centrilobular cells based on chemical quantitation