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In addition, GPX4 activators can also be applied in a series of biological processes where GPX4 is involved, especially in ferroptosis control

While many of these animal studies investigated alterations in gene expression (135140) and DNA damage (141, 142) upon irradiation, in this review we focus on the morphological, biochemical, metabolic, and protein changes that characterise the cataract phenotype induced as a result of UV-A or UV-B exposure

For instance, they secrete anti-inflammatory cytokines such as IL-10, which suppresses T-cell activation and promotes the differentiation of regulatory T cells (Tregs), further enhancing tolerance (39, 40)

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