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The big downside here comes during the loading phase, a period lasting 5-7 days and usually involving between 10g and 30g of creatine per day, which translates to an impractical number of capsules by the end of the week you could burn through an entire bottle in two days!3 So, this product is better for lower-dose maintenance after a loading phase or for those who prefer to skip the loading phase and drop straight into maintenance
In contrast, the striatum has enlarged in parallel with the cerebral cortex throughout evolution and it is particularly well-developed in higher mammals, including humans
these typically decrease over time
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