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This extracellular and mislocalized intracellular copper exacerbates DCM through multiple pathways, activating the TGF-/Smad signaling pathway and amplifying oxidative stress, collectively promoting extracellular matrix deposition and fibrotic remodeling [171]

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Summary Keywords abiotic stress, arsenic, detoxification, glutathione, heavy metals, oxidative stress Citation Kumar S and Trivedi PK (2018) Glutathione S-Transferases: Role in Combating Abiotic Stresses Including Arsenic Detoxification in Plants

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