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Because oral dosing delivers the peptide directly to this tissue at high local concentration, it is the logical first choice for objectives like reflux-related irritation, inflammatory bowel-type inflammation, leaky-gut concerns, and general intestinal lining repair

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Reduces inflammation, promotes tissue repair, and accelerates healing

In contrast to EAE where the primary stimulus is immune upregulation in the presence of extrinsic myelin antigens, the CAE model illustrates that MS-like pathology can also be generated by an upstream intrinsic myelin injury, releasing antigens which secondarily trigger white matter inflammation in an immune-predisposed host