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GLP-1 agonists are generally well tolerated, but like any medication, they can cause side effects

Anxiety itself activates the sympathetic nervous system, genuinely increasing heart rate and creating a self-perpetuating cycle

Treatment by exogenous ethylene, as a common postharvest practice to trigger the ripening of mature green fruits before placing them on the shelf, caused a 24% and 51% folate increase in tomatoes and bananas, resp., a 26% folate decrease in papayas, and no change in avocados, compared to non-treated fruits 531