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Nature 504 , 394400 (2013)

This exceptional selectivity profile enables researchers to attribute observed effects specifically to NNMT inhibition, rather than off-target activities that plague less specific compounds

Potential applications of amino acid metabolism regulation in the diagnosis and treatment of IPF Amino acids as emerging biomarkers in IPF Although traditional biomarkers such as KL-6, SP-D, MMP-7, TIMPs, and CCL18 remain commonly used in IPF diagnosis and monitoring [130], emerging evidence suggests that amino acid metabolic profiles may offer valuable diagnostic and prognostic insights

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