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However, in the United States, about 10% of patients develop persistent synovitis, which lasts for months or even several years after the apparent eradication of the spirochete from joints with antibiotic therapy

The interaction of ApoE4 with oligomers and fibrils of A has been found to impact the kinetics of amyloid aggregation, indicating that ApoE4 stabilizes soluble, cytotoxic oligomeric A fragments, thereby enhancing fibril formation and promoting A deposition (Garai et al., 2014)

Coming up: The Sixers have the third toughest remaining schedule (cumulative opponent winning percentage of .500) among the top eight teams in the East, though only 10 of their 22 games are against teams that currently have winning records

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