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The intention to treat analysis indicated that at three months the proportion of successes in each group defined by the Global Response Assessment (GRA)as moderate or marked improvement were statistically similar (drug 55%

hCiPSC administration reduced characteristic ASD-associated genera including Ruminococcus, Clostridium, and Turicibacter, though full restoration of beneficial taxa was not achieved

In contrast to the ROP, depolymerization of the disulfide bonds required harsher conditions and more time 13,19