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FIGURE 4 This is complicated because as a polar, charged tripeptide, transport of GSH is significantly inhibited by the blood-brain barrier (BBB), thus limiting effective delivery to brain-resident immune cells such as microglia which are central drivers of neuroinflammatory pathology ( As many treatments for neurological conditions have been hampered by limited permeability of the BBB, significant emphasis has been placed on research directed towards advanced drug delivery methods (Zha et al., 2024

Overall, use of DMSO should be avoided where possible

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Ce que disent les tudes cliniques sur l'effet claircissant Plusieurs essais randomiss contrls contre placebo ont valu l'effet du glutathion oral sur la pigmentation cutane