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Clinicians should consider several potential concerns during evaluation: Unknown active ingredient source Variable potency or concentration Differences in excipients Sterility concerns for injectable products Dosing inaccuracies Limited stability data Inconsistent patient instructions The FDA has also warned healthcare professionals about compounded products made with salt forms of semaglutide that differ from the approved active ingredient

Schimmer AD, Gronda M, Wang Z, Welsh K, Pinilla C, Andreeff M , Schober WD, Nefzi A, Houghten R, Brandwein J, Minden MD, Schuh A, Wells RA, Messner H, Reed JC, Carter BZ

Discard the pen Disposing of single-dose Mounjaro injection pens properly is critical to preventing harm to kids, animals, or anyone else in the house

Inadequate Response to Oral Medications Patients who have tried and failed to achieve target blood sugar levels with oral medications such as metformin, sulfonylureas, or thiazolidinediones may be considered for GLP-1 therapy