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iii) A ROS-responsive hydrogel matrix (G) has been synthesized, exhibiting superior ROS-scavenging capabilities, functioning as an intelligent drug reservoir that enables the controlled release of D-CuP at the wound interface while simultaneously attenuating inflammatory responses in the microenvironment 51

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GHK-Cu is sold as a research compound and is not FDA-approved for human use

Thus, designing an all-rounder with space-time ROS scavenging, modulation of macrophage polarization, and promotion of angiogenesis and cell proliferation is a prominent subject for advancing the clinical treatment of chronic diabetic wounds