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Activation of Telomerase Reverse Transcriptase (TERT) Downregulation of HER-2/neu Expression Biological Activity Epithalon has been shown to increase lifespan in rodent models, reduce spontaneous and induced tumor formation, stabilize the genome by reducing chromosomal aberrations, and modulate immune cell proliferation

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Informed Consent and Patient Education Informed consent discussions for BPC-157 use should clearly communicate the investigational nature of the peptide, lack of FDA approval, limited human safety and efficacy data, and the reliance on animal studies for much of the supporting evidence