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This is also consistent with a higher PLCE1 gene expression in the normal colorectal tissues as compared to the colorectal adenocarcinoma in the Oncomine cancer microarray dataset (Figure 2D)

The Grant of Excellence Departments, MUR (ARTICOLO 1, COMMI 314 337 LEGGE 232/2016) to the Department of Science, Roma Tre University

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Overall, the published data support the idea that multi-layered endogenous antioxidant defense mechanisms in the liver limit the occurrence of pathophysiologically relevant LPO under normal conditions