In clinical trials, 14% of people taking the highest dose of Wegovy reported headache as a side effect compared to 10% of the placebo group
Early case series and open-label studies support feasibility and biological plausibility, whereas randomized trials show mixed clinical signals, highlighting donor-dependent effects, protocol heterogeneity (preconditioning, route, dose/frequency), and the need for engraftment-aware endpoints [252,253,254,255]
General precautions: Always take it under doctor's supervision Tell your doctor if you're pregnant or breastfeeding Don't skip doses randomly, consistency matters Store tablets away from heat and moisture Medical conditions to mention: Kidney disease Any ongoing allergy history Leber's disease (a rare eye condition, B12 can worsen it) Drug interactions: Some antibiotics and metformin can reduce B12 absorption Always share your full medicine list with your doctor When to Consult a Doctor
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