barbarum dates back over 4,000 years, with its earliest mention in the ancient text Shen Nong Ben Cao Jing (The Classic of Herbal Medicine), written between 200 and 250 AD

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Even the simple administration of bromelain in mice challenged with 4T1 triple-negative breast cancer cells can increase the effectiveness of anticancer drugs with severe side effects
A synthetic analogue of growth hormonereleasing hormone (GHRH), consisting of 44 amino acids