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The melanosomes in melanocytes residing in the basal cell layer of the epithelium can synthetise two chemically distinct types of melanin: brown/black eumelanin and red/yellow pheomelanin, both of which are derivatives of the amino acid tyrosine through the intermediate step of conversion of dopa to dopamine [4]

As noted in previous discussions related to Study 1419 and the EU-IGFD Registry, results for outcomes based on SDSs can differ depending on the reference standard used

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