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Faima Atta Khan, Fahad AlAsmari, and Muhammad Abdul Rahim conceptualized design of the work, data analysis, aided in drafting manuscript

Although its function continues to be elucidated, SELENOF was found to interact with the endoplasmic reticulum UDP-glucose:glycoprotein glucosyltransferase (UGGT), an enzyme involved in the quality control of glycoprotein folding in the endoplasmic reticulum (30, 31)

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This is the point where most clinicians evaluate whether to continue, switch approaches, or cycle off