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Thus, disturbances in mitochondrial ICS biosynthesis could contribute to failures in the supply of energy (which might result in cell death) or to cancer, since genomic instability is considered as a hallmark of cancer and a driver of neoplastic transformation processes

To assess whether the findings could be explained by GLP-1 RA-related weight loss, we conducted a counterfactual analysis in which we set pre-pregnancy BMI to values consistent with a scenario without treatment-related weight reduction and repeated the analyses

95% CI, 0.69-0.98)