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Results: Significant reduction in modified MASI was observed in patients treated with topical and oral glutathione ( p =0.011) and ( p =0.007) respectively, while patients treated with topical or oral placebo had no response

Later, Pearce (1940) discovered that this oxidation is catalyzed by hydrogen peroxidase, therefore, the oxidation of iodide is a secondary oxidation reaction by hydrogen peroxide formed as a result of oxidation of glucose catalyzed by glucose oxidase