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Perchloric acid (PCA) and trichloroacetic acid (TCA) were obtained from Merck (Darmstadt, Germany)

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A few studies have failed to show such OS changes in dogs with cardiac conditions, possibly due to the specific biomarkers studied, non-linear changes in oxidation across stages of MMVD or DCM, or potential antioxidant effects of some therapeutic agents such as benazepril or sildenafil, which have yet to be conclusively studied [32,39,42]