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Oxidative stress, driven by excessive production of reactive oxygen species (ROS), leads to damage of neuronal lipids, proteins, and DNA (Guo et al., 2020)

A 10-week MeDi intervention in World Trade Center responders with PTSD significantly reduced inflammatory markers such as CRP and lessened PTSD symptom severity compared to standard nutritional advice ( Eubacterium eligens , a short-chain fatty acid producer from dietary fiber, coinciding with lower PTSD severity, indicating that Mediterranean dietary patterns may support gut-mediated neuroprotection (Ke et al., 2023)

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Glutathione binds a huge number of lipophilic compounds (physical neutralization), preventing their introduction into the lipid layer of membranes and disruption of cell functions