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Inhibition of this enzyme can lead to pellagra, which, in these cases, may present with cerebellar signs, myoclonus, and ataxia (55)

Based on preclinical data and community reports, minimum 3 to 6 months of consistent use is needed before evaluating effectiveness

117 Considering the core role of CMA in maintaining cellular homeostasis and delaying aging, intervention strategies targeting CMA may provide new strategies for the treatment of age-related diseases