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These results were consistent with the per protocol analysis (Figure 2)

A key rationale for screening children and young adults is that early and intensive intervention will reduce future morbidity and mortality [20]

No serious adverse reactions were reported [8]

The optimal dosing sequence is 5-Amino-1MQ first (50100mg fasted), followed by MOTS-c 46 hours later (510mg), allowing NAD+ replenishment before increased mitochondrial demand