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Comparative effectiveness and safety of medications for type 2 diabetes: an update including new drugs and 2-drug combinations

While the numbers we estimate are for Great Britain as a whole, it is noteworthy that the number using these medications for weight loss far exceeds the initial expectation for NHS England to provide treatment for 220,000 people in the first 3 years, which is likely to have important consequences for NHS budgets, although our estimate is less than the number eligible according to NICE guidelines (3.4 million) [14]

This is not about replacing or enhancing the medication itself