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Conner Mertens 02:28 Well, I mean, it sounds like this is a pretty complex study, a lot of big numbers, a lot of moving parts

Preclinical studies have shown that GLP-1 receptor activation can reduce alcohol-induced dopamine release, leading to reduced alcohol-seeking behavior in animal models (Vallf et al., 2019)

They also noted that glucagon-like peptide-1 receptor agonists are already being prescribed off-label for alcohol use disorder despite limited evidence

The rebate economics that incentivize co-placement are a function of fee structure, not deliberate obstruction, though the practical effect is identical