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Evidence Quality Summary Honest appraisal of the evidence hierarchy for this stack: | Claim | Evidence Level | |---|---| | Ipamorelin raises GH via GHSR-1a | Strong: mechanistic + animal + human Phase I | | CJC-1295 raises GH and IGF-1 in humans | Moderate: Phase II RCT (N=65) | | Combination produces synergistic GH pulses | Moderate in animals

CrossRef Functional and morphometric assessment of small-fibre damage in late-onset hereditary transthyretin amyloidosis with polyneuropathy: the controversial relation between small-fibre-related symptoms and diagnostic test findings Eleonora Galosi, Luca Leonardi, Pietro Falco, Giuseppe Di Pietro, Alessandra Fasolino, Nicoletta Esposito, Caterina Leone, Giulia Di Stefano, Maurizio Inghilleri, Marco Luigetti, Antonini Giovanni, Andrea Truini Amyloid.2023