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Differences in metabolic profiles at baseline and post-treatment were noted between participants who remitted (HRSD 17 7) and those who gained no meaningful benefits ( 14 on HRSD 17 were eligible for inclusion in the trial
More serious but uncommon side effects are typically linked to high or frequent dosing
In response to oxidative stress, this regulatory mechanism allows NRF2 to rapidly translocate to the nucleus and activate transcription of antioxidant and phase II detoxifying enzymes to effectively mitigate external insults (Figure 2)
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