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In clinical trials of Wegovy (a semaglutide medication), participants lost an average of 15% of their body weight (approximately 33 pounds, though individual results varied) within 68 weeks

Anderson JV, Davis DG (2004) Abiotic stress alters transcript profiles and activity of glutathione S-transferase, glutathione peroxidase, and glutathione reductase in Euphorbia esula