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Risk factors that increased the likelihood of developing NAION included a history of DR, insulin use, male sex, white race, dual eligibility in Medicare and Medicaid, rural residency, sleep apnea and concurrent use of amiodarone and GLP-1 agonists

Dosing frequency and titration schedules play a crucial role: medications that allow for gradual dose escalation over several weeks enable the gastrointestinal system to adapt more effectively to the delayed gastric emptying effect

10.1016/j.ijbiomac.2023.125754 324 TangW.WangJ.HouH.LiY.WangJ.FuJ.et al (2023a)

Generally, the effects of a Glutathione injection can last anywhere from two to three weeks