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Genome-wide association studies (GWAS) coupled with metabolomic profiling has provided novel insights the role of inherited variation in blood metabolic diversity and potential opportunities for novel drug development in T2D (Shin S

Arrhythmias often occur in people who have some form of underlying heart disease, such as coronary artery disease, but a healthy heart is not immune to abnormal heart rate or rhythm (UoMMC 2012

Apart from TRPC channels, a role for ionotropic glutamate receptors for Ca 2+ entry has been suggested: NMDA receptors permeable to Ca 2+ accomplish Ca 2+ homeostasis [102, 103], and also AMPA receptors may be relevant as pharmacological AMPA receptor antagonism blunts Ca 2+ entry into erythrocytes in response to Cl - removal [104]

1 Education for awareness and health care and control of hyperglycemia, dyslipidemia and hypertension are key strategies for slowing the onset and worsening of DR, similar to other MDS-related complications