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Among the gene sets, genes with roles in GSH metabolism (KEGG_GLUTATHIONE_METABOLISM, p value, 0.032) were substantially downregulated in Fabry kidney organoids, indicating that the molecular functions were relatively deactivated

Kothare PA, Linnebjerg H, Skrivanek Z, Reddy S, Mace K, Pena A, et al

37 RCTs Meta-Analysis (2020) Weight loss: -1.13 kg BMI: -0.36 points Fat mass: -1.16 kg Waist circumference: -1.24 cm Umbrella Meta-Analysis (2025) Confirms: statistically significant weight loss , especially combined with exercise

Source: Sikiric et al., Curr Pharm Des 2018