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For those wondering about the differences between semaglutide, tirzepatide, and retatrutide , the data shows a clear hierarchy of efficacy forming among incretin-based therapies

The mechanism involves glycine acting on NMDA receptors in the suprachiasmatic nucleus, the brain region that controls your circadian clock

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Side effects for GLP-1s may include nausea, vomiting, stomach pain, upset stomach, dizziness, constipation, feeling bloated, belching, gas, headaches and fatigue