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2- Cardiovascular Protection : Improves multiple risk markers, lowers heart failure, related outcomes, and reduces progression[7] to type 2 diabetes in high-risk populations

In an evidence-based approach, the key points contributing to this consensus with respect to the clinical impact and benefits of GLP-1 RAs and their use in special populations are as follows: Clinical impact of GLP-1 RAs: GLP-1 RAs improve glucose homeostasis by enhancing glucose-dependent insulin secretion, by suppressing inappropriately elevated glucagon levels, both in fasting and postprandial states (Grade A

[DOI] [PMC free article] [PubMed] [Google Scholar] 194.Yancy W.S., Jr., Crowley M.J., Dar M.S., Coffman C.J., Jeffreys A.S., Maciejewski M.L., Voils C.I., Bradley A.B., Edelman D

Compounded tirzepatide is not an FDA-approved brand-name drug